李建树,付聪.温针灸联合舒络通脉汤治疗寒凝血瘀型糖尿病周围神经病变疗效分析[J].中医药信息,2025,42(4):40-44 |
温针灸联合舒络通脉汤治疗寒凝血瘀型糖尿病周围神经病变疗效分析 |
Therapeutic Efficacy of Warm Acupuncture Combined with Shuluo Tongmai Decoction in Treating Diabetic Peripheral Neuropathy of Cold Congealing and Blood Stasis Type: A Clinical Analysis |
投稿时间:2024-04-08 录用日期:2024-05-11 |
DOI:10.19656/j.cnki.1002-2406.20250407 |
中文关键词: 温针灸 舒络通脉汤 寒凝血瘀型 糖尿病周围神经病变 |
英文关键词: Warm acupuncture Shuluo Tongmai Decoction Cold coagulation and blood stasis type Diabetic peripheral neuropathy |
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中文摘要: |
目的:观察温针灸联合舒络通脉汤治疗寒凝血瘀型糖尿病周围神经病变(DPN)的临床疗效及对神经传导速度、同型半胱氨酸(Hcy)、胱抑素C(CysC)的影响。方法:选择符合纳入标准的寒凝血瘀型DPN患者80例,依据随机数字表随机分为治疗组和对照组,每组各40例。对照组给予硫辛酸注射液,治疗组在对照组基础上给予温针灸联合舒络通脉汤足浴,两组治疗时间均为14 d。比较两组患者治疗前后中医症状积分、神经传导速度、同型半胱氨酸(Hcy)、胱抑素C(CysC)、多伦多临床评分系统(tronto clinical scoring system,TCSS)评分的变化情况,并进行安全性监测。结果:两组治疗后中医症状积分均显著降低(P < 0.05),且治疗组低于对照组(P < 0.05);治疗后两组患者神经传导速度均显著提高(P < 0.05),且治疗组显著高于对照组(P < 0.05);治疗后两组患者Hcy、CysC水平均显著降低(P < 0.05),但两组之间比较差异无统计学意义(P > 0.05);治疗后两组患者TCSS积分均降低(P < 0.05),且治疗组低于对照组(P < 0.05);治疗组总有效率为92.5%(37/40),对照组总有效率67.5%(27/40),治疗组显著高于对照组(P < 0.05);治疗期间,两组均无不良反应发生。结论:温针灸联合舒络通脉汤足浴治疗寒凝血瘀型DPN,可有效缓解临床症状和体征,改善神经传导速度,安全性较好。 |
英文摘要: |
Objective: To observe the clinical efficacy of warm acupuncture combined with Shuluo Tongmai Decoction in treating diabetic peripheral neuropathy (DPN) of cold coagulation and blood stasis type, and its impact on nerve conduction velocity, homocysteine (Hcy), and cystatin C (CysC). Methods: Eighty patients with cold coagulation and blood stasis type DPN who met the inclusion criteria were selected and randomly assigned into treatment and control groups, with 40 cases in each group. The control group received injections of alpha-lipoic acid, while the treatment group received warm acupuncture combined with foot baths of Shuluo Tongmai Decoction in addition to alpha-lipoic acid. Both groups were treated for 14 days. Changes in traditional Chinese medicine symptom scores, nerve conduction velocity, Hcy, CysC levels, and Toronto Clinical Scoring System (TCSS) scores before and after treatment were compared between the two groups, with safety monitoring conducted. Results: Both groups showed significant decreases in traditional Chinese medicine symptom scores after treatment (P < 0.05), with greater improvement in the treatment group compared to the control group (P < 0.05). Nerve conduction velocities in both groups significantly increased after treatment (P < 0.05), with the treatment group showing greater improvement compared to the control group (P < 0.05). Levels of Hcy and CysC significantly decreased after treatment in both groups (P < 0.05), with no statistically significant difference between the groups (P > 0.05). TCSS scores decreased significantly in both groups after treatment (P < 0.05), with the treatment group showing lower scores compared to the control group (P < 0.05). The total effective rate was 92.5% (37/40) in the treatment group and 67.5% (27/40) in the control group, with a significant difference favoring the treatment group (P < 0.05). No adverse reactions were observed in either group during the treatment period. Conclusion: Warm acupuncture combined with Shuluo Tongmai Decoction foot baths effectively alleviates clinical symptoms and signs, improves nerve conduction velocity, and demonstrates good safety in treating cold coagulation and blood stasis type DPN. |
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