独活续断汤联合穴位埋线治疗腰椎间盘突出症的临床研究

李晓飞；王培霞；杨洋

文章摘要

李晓飞；王培霞；杨洋.独活续断汤联合穴位埋线治疗腰椎间盘突出症的临床研究[J].中医药信息,2023,40(9):62-65

独活续断汤联合穴位埋线治疗腰椎间盘突出症的临床研究

Clinical Study of Duhuo Xuduan Decoction Combined with Catgut Embedment in Acupoint for the Treatment of Lumbar Disc Herniation

投稿时间：2022-11-21 录用日期：2022-12-29

DOI：10.19656/j.cnki.1002-2406.20230910

中文关键词: 独活续断汤穴位埋线腰椎间盘突出症腰椎关节活动度 CRP IL－6 TNF－α

英文关键词: Duhuo Xuduan decoction Catgut embedment in acupoint Lumbar disc herniation Range of lumbar joint motion CRP IL－6 TNF－α

基金项目:

作者	单位
李晓飞；王培霞；杨洋

摘要点击次数: 105

全文下载次数: 140

中文摘要:

目的：探讨独活续断汤联合穴位埋线治疗腰椎间盘突出症的临床疗效。方法：选取符合纳入标准的腰椎间盘突出症患者120例，依据随机数字表随机分为观察组和对照组，每组各60例。对照组给予穴位埋线治疗，观察组在对照组治疗基础上给予独活续断汤治疗，两组患者均治疗30 d。比较两组患者治疗前后腰椎关节活动度（腰椎前屈、腰椎后伸）、Oswestry功能障碍指数（Oswestry disability index,ODI）、视觉疼痛评分（visual analogue scale,VAS）、日本骨科协会评估治疗评分（Japanese Orthopaedic Association scores,JOA）、血清炎性因子[C反应蛋白（C reactive protein,CRP）、白介素-6(interleukin-6,IL-6)和肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)]水平和不良反应情况，比较两组临床疗效。结果：与对照组比较，观察组患者治疗总有效率（95%,57/60）明显高于对照组（81.67%,49/60）（χ2=5.175,P <0.05）。治疗后，两组患者腰椎前屈度、腰椎后伸度均上升，且观察组优于对照组（t=4.813、5.151,P <0.01）；两组患者ODI、VAS评分均下降，JOA评分上升，且观察组优于对照组（t=-11.295、-8.487、18.650,P <0.01）；两组患者CRP、IL-6、TNF-α水平均下降，且观察组下降较对照组更显著（t=-18.435、-8.986、-11.644,P <0.01）。治疗过程中，观察组1例患者出现体温升高，对照组1例患者出现头晕、1例患者出现皮疹，3位患者均在未进行干预的情况下于1 d后自行好转，两组患者不良反应发生率比较差异无统计学意义（P> 0.05）。结论：独活续断汤联合穴位埋线可显著提高腰椎间盘突出症的治疗效果，减轻腰椎功能障碍程度，改善炎性反应。

英文摘要:

Objective: To explore the clinical effects of Duhuo Xuduan decoction combined with catgut embedment in acupoint on the treatment of lumbar disc herniation. Methods: 120 patients with lumbar disc herniation who met the inclusion criteria were selected and randomly divided into an observation group and a control group based on a random number table, with 60 patients in each group. The control group was treated with catgut embedment in acupoint, and the observation group with catgut embedment in acupoint plus Duhuo Shuduan decoction, for 30 days. Before and after the treatment, we compared, between the two groups, the lumbar joint range of motion(lumbar flexion, lumbar extension), Oswestry disability index(ODI), visual analogue score(VAS), Japanese Orthopedic Association scores(JOA), levels of serum inflammatory factors [C-reactive protein(CRP), interleukin-6(IL-6) and tumor necrosis factor-α(TNF-α)], and adverse reaction. The treatment effects were also compared between the two groups. Results: Compared with the control group(81. 67%,49/60), the total effective rate of patients in the observation group(95. 00%, 57/60) was significantly higher(χ2 = 5. 175,P < 0. 05). After the treatment, the lumbar forward flexion and lumbar posterior extension increased in both groups, and the observation group is superior to the control group(t = 4. 813, 5. 151, P < 0. 01). The scores of both ODI and VAS in the two groups decreased, while the JOA scores increased, and the changes in the observation group are superior to the control group(t =-11. 295,-8. 487, 18. 650, P < 0. 01). The levels of CRP, IL-6, and TNF-α all decreased, especially in the observation group(t =-18. 435,-8. 986,-11. 644, P < 0. 01). During the treatment, 1 patient in the observation group had elevated temperature, 1 patient in the control group developed dizziness, 1 patient developed skin rash, and the 3 patients improved 1 day later without intervention. There was no statistically significant difference in the incidence of adverse reactions between the two groups(P > 0. 05). Conclusion: Duhuo Shuduan decoction combined with catgut embedment in acupoint can significantly improve the therapeutic effect on lumbar disc herniation, reduce the degree of lumbar dysfunction, and improve inflammatory reaction.

查看全文查看/发表评论下载PDF阅读器

关闭