| 巩明霞;孔祥图;于慧;陈晓丽;倪海雯.淋巴瘤中医证候量表的研制与测评[J].中医药信息,2023,40(8):51-58 |
| 淋巴瘤中医证候量表的研制与测评 |
| Development and Evaluation of Chinese Medicine Syndrome Scale for Lymphoma |
| 投稿时间：2022-12-04 录用日期：2023-01-11 |
| DOI：10.19656/j.cnki.1002-2406.20230808 |
| 中文关键词: 条目筛选 淋巴瘤 中医证候量表 疗效评价 |
| 英文关键词: Item selection Lymphoma Traditional Chinese medicine syndrome scale Efficacy evaluation |
| 基金项目:江苏省中医药管理局课题 |
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| 中文摘要: |
| 目的：以国医大师周仲瑛教授癌毒学说为基础，结合真实世界淋巴瘤的症状及病机要素，设计淋巴瘤中医证候量表。方法：通过查阅淋巴瘤中医证候学和症状学相关文献，结合淋巴瘤临床症状数据挖掘结果，形成量表条目池。选取江苏省中医院的淋巴瘤患者进行正式调查，分别从离散趋势法、克朗巴赫系数法、因子分析法、相关系数法4个方面考评量表的信效度。结果：共纳入受试者129例，应用以上统计方法对调查结果进行分析、汇总，删除未通过筛选的条目，确定了包含5个维度、25个条目的终选量表。结论：本研究初步形成的疗效评价量表具有良好的信效度，可客观指导中医临床治疗，为高级别临床证据的产生提供依据。 |
| 英文摘要: |
| Objective: To design traditional Chinese medicine syndrome scale for lymphoma based on the theory of cancer toxicity of Professor Zhou Zhongying, and combining the symptoms and pathogenesis factors of lymphoma in the real world. Method: The scale item pool was established by consulting the literature related to TCM syndromes and symptomatology of lymphoma, and combining with the data mining results of lymphoma clinical symptoms. Lymphoma patients were selected from Jiangsu Province Hospital of Chinese Medicine for formal investigation. The reliability and validity of the scale were evaluated from four aspects: discrete trend method, Cronbach's alpha method, factor analysis method, and correlation coefficient method. Result: A total of 129 patients were included, and the survey results were analyzed and summarized using the above statistical methods. Items that did not pass the screening were deleted, and a final scale consisting of 5dimensions and 25 items was determined. Conclusion: The preliminary efficacy evaluation scale developed in this study has good reliability and validity, which can objectively guide the clinical treatment of traditional Chinese medicine and provide a basis for the generation of high-level clinical evidence. |
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