| 阮娟娟；魏霞；孔艳芳；秦合伟.头针带针康复疗法治疗缺血性脑卒中后认知功能障碍的临床疗效观察[J].中医药信息,2024,41(6):50-54 |
| 头针带针康复疗法治疗缺血性脑卒中后认知功能障碍的临床疗效观察 |
| Clinical Observation of Therapeutic Effect of Scalp Acupuncture with Long Time Needle Retention Rehabilitation on Cognitive Impairment after Ischemic Stroke |
| 投稿时间：2023-09-04 录用日期：2023-10-26 |
| DOI：10.19656/j.cnki.1002-2406.20240609 |
| 中文关键词: 脑卒中 认知功能障碍 头针 带针康复 |
| 英文关键词: Stroke Cognitive impairment Scalp acupuncture Scalp-acupuncture with long time needle retention rehabilitation |
| 基金项目:1.河南省中医药科学研究专项课题(课题编号：2023ZY2068)，2.河南省中医学“双一流”创建科学研究专项课题（HSRP-DFCTCM-2023-3-27），3.河南省中医药拔尖人才培养项目资助(编号：豫卫中医函[2021]15号)。 |
|
| 摘要点击次数: 63 |
| 全文下载次数: 53 |
| 中文摘要: |
| 目的：观察头针带针康复疗法治疗缺血性脑卒中后认知功能障碍的临床疗效。方法：选取符合纳入标准的100例缺血性脑卒中后认知功能障碍患者，依据随机数字表随机分为观察组和对照组，每组各50例。对照组采用基础治疗、认知功能训练法和普通头针疗法，观察组在常规基础疗法、常规认知功能康复训练方法基础上采用头针带针康复疗法，两组均治疗6周。采用简易智能精神状态量表（MMSE）和蒙特利尔认知评估量表（MoCA）评价患者认知功能改善情况；ELISA法检测血清CGRP和5-HT水平；ELISA法检测患者血清胰岛素样生长因子-1(IGF-1)和心型脂肪酸结合蛋白（HFABP）水平；采用尼莫地平法进行有效率评价。结果：治疗后，观察组患者MMSE和MoCA评分明显高于治疗前（P <0.05），且观察组高于对照组（P <0.05）；两组患者CGRP和5-HT水平明显高于治疗前（P <0.05），且观察组CGRP和5-HT水平明显高于对照组（P <0.05）；两组患者血清IGF-1和H-FABP水平均明显降低（P <0.05），且观察组IGF-1和H-FABP水平明显低于对照组（P <0.05）；观察组总有效率96%(48/50)明显高于对照组总有效率80%(40/50)(P <0.05)。结论：头针带针康复疗法治疗缺血性脑卒中后认知功能障碍，能够明显改善患者认知功能，调控认知相关神经递质，减轻神经损伤。 |
| 英文摘要: |
| Objective: To observe the clinical effect of scalp acupuncture with long time needle retention rehabilitation therapy on cognitive dysfunction after ischemic stroke. Methods: A hundred patients with cognitive dysfunction after ischemic stroke meeting the inclusion criteria were randomly divided into observation group and control group according to a random number table, with 50 cases in each group. The control group was treated with basic therapy, cognitive function training and ordinary scalp acupuncture, and the observation group was treated with basic therapy, cognitive function training and scalp acupuncture with long time needle retention. Both groups were treated for 6 weeks. The patients' cognitive function was evaluated by the Mini-Mental State Examination(MMSE) and the Montreal Cognitive Assessment(MoCA).Serum levels of CGRP, 5-HT, insulin-like growth factor-1(IGF-1) and heart fatty acid-binding protein(H-FABP) were detected by ELISA. The effective rate was evaluated by nimodipine method. Results: After treatment, MMSE and MoCA scores in observation group were significantly higher than before treatment(P <0. 05), and those in observation group were higher than those in control group(P < 0. 05). CGRP and 5-HT levels in 2 groups were significantly higher than before treatment(P < 0. 05), and they were significantly higher in observation group than in control group(P < 0. 05). Serum IGF-1 and H-FABP levels in 2groups significantly decreased(P < 0. 05), and they were significantly lower in observation group than in control group(P < 0. 05). The total effective rate of the observation group was 96%(48/50), which was significantly higher than that of the control group(80%(40/50)(P < 0. 05). Conclusion: Scalp-acupuncture with long time needle retention rehabilitation therapy for cognitive dysfunction after ischemic stroke can significantly improve the cognitive function of patients, regulate cognitive-related neurotransmitters, and reduce nerve damage. |
|
查看全文
查看/发表评论 下载PDF阅读器 |
| 关闭 |
