| 关枫；任欠欠；付起凤；刘磊；崔明宇；王艳宏.火麻仁中水溶性活性蛋白质与糖类成分的研究进展[J].中医药信息,2024,41(3):85-89 |
| 火麻仁中水溶性活性蛋白质与糖类成分的研究进展 |
| Research Progress on Water－Soluble Active Proteins and Saccharides from Cannabis Fructus |
| 投稿时间：2024-01-23 录用日期：2024-03-05 |
| DOI：10.19656/j.cnki.1002-2406.20240314 |
| 中文关键词: 火麻仁 活性蛋白质 水溶性总糖 制备工艺 药理作用 |
| 英文关键词: Cannabis Fructus Active proteins Water－soluble total sugars Preparation process Pharmacological action |
| 基金项目:黑龙江省中医药管理局项目(ZYW2022-067)；黑龙江省“头雁”团队项目([2019]No.5)。 |
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| 中文摘要: |
| 火麻仁为药食同源中药，应用历史久远，含有丰富的火麻油、大麻素类、木脂素酰胺类、火麻蛋白、多糖等成分，具有润肠通便的功效，在食品和医药领域都表现出较好的开发前景。笔者通过查阅近10年火麻仁的相关文献报道，对其主要水溶性活性蛋白质与糖类的最新研究进行了分析整理，发现火麻仁蛋白是一种优质的植物蛋白，主要由天冬氨酸、精氨酸、赖氨酸等氨基酸构成，具有通便、抗疲劳、抗衰老、抗氧化等药理作用，可通过碱提（酸沉）法、盐析法、酶解法等方法提取纯化，毒理学研究证实其应用较为安全；火麻仁中水溶性总糖含量约为3%～6%，主要具有免疫调节及抗氧化作用，可通过微波辅助提取进行制备，但相关单糖组成、糖链连接等结构研究还未深入开展。 |
| 英文摘要: |
| Cannabis fructus （CF） has been a traditional Chinese medicine for a long time， and can be used both as food and medicine. It contains rich hemp oil， cannabinoids， lignan amides， hemp protein， polysaccharide and other components， and has the effect of moistening and relaxing bowel， showing a good development prospect in food and medicine fields. The authors of this paper have analyzed and sorted out the research in the past 10 years on the main water－soluble active proteins and saccharides of Cannabis fructus by reviewing relevant literatures. It is found that Cannabis fructus protein is a kind of high quality plant protein， mainly composed of aspartate， arginine， lysine and other amino acids， which has pharmacological effects such as laxative， anti－fatigue， anti－aging， anti－oxidation， etc. It can be extracted and purified by alkali extraction （acid precipitation）， salt precipitation， enzymatic hydrolysis， and other methods， and toxicological studies have confirmed that its application is relatively safe. The total water－soluble sugar content in CF is about 3%～6%， which mainly has immune regulation and antioxidant effects， and can be prepared by microwave assisted extraction. However， the related monosaccharide components and sugar chain linkage structure have not been deeply studied. |
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