文章摘要
苏晓悦,徐驰,杜鑫,王震,张美琦,任伟超,刘秀波,马伟.白头翁化学成分及其药理作用研究进展[J].中医药信息,2023,40(3):76-82
白头翁化学成分及其药理作用研究进展
Research Progress in Chemical Constituents and Pharmacological Effects of Pulsatilla chinensis
投稿时间:2022-11-15  录用日期:2022-12-06
DOI:
中文关键词: 白头翁  化学成分  药理作用  研究进展
英文关键词: Pulsatilla chinensis  chemical constituents  pharmacological effects  research progress
基金项目:黑龙江省中医药管理局“中医药经典普及化专项课题”项目(ZYW2022-033); 国家重点研发计划课题项目(2021YFD1600901)
作者单位
苏晓悦,徐驰,杜鑫,王震,张美琦,任伟超,刘秀波,马伟  
摘要点击次数: 417
全文下载次数: 320
中文摘要:
      白头翁为临床常用中药,主治热毒血痢、阴痒带下、肛门灼热等。本文综述国内外相关文献资源,发现白头翁含有很多种化学成分,例如三萜皂苷类、三萜酸类、香豆素类、木脂素类、脂肪酸类以及小分子类等,具有非常高的药用价值和广泛的应用前景。在临床上可用于治疗肠炎、肺炎、肿瘤、流感以及肝损伤等,具有抗肿瘤、抗病毒、抗炎、抗阴道毛滴虫、抑菌杀菌、杀精、抗氧化、抗诱变、保护肝脏、增强免疫功能以及影响细胞增殖和凋亡等作用。但白头翁除三萜皂苷类以外的其他化学成分并未得到深入的研究,部分药理作用如抗氧化、杀精以及对免疫功能和细胞调控的影响等方面并未在临床上得到很好的挖掘和应用。
英文摘要:
      As a commonly used traditional Chinese medicine in clinical practice, Pulsatilla chinensis contains a variety of chemical components, such as triterpene saponins、triterpene acid、coumarin、lignans、fatty acid and Small molecules, etc. It has very high medicinal value and wide application value which can be used to treat enteritis, pneumonia, tumors, influenza and liver damage in the clinic. Modern pharmacological research has found that P.chinensis has the effect of anti-inflammatory, antiviral, anti-vaginal trichomoniasis, bacteriostatic and bactericidal, antitumor, antioxidant, anti-mutagenesis, spermicide, liver protection, enhancing immune function, affecting cell proliferation and apoptosis. This study reviews the existing literature resources, then summarizes the chemical composition and pharmacological effects of P.chinensis systematically and comprehensively, so as to establish the drug standard of P.chinensis, optimize the quality evaluation system of P.chinensis, find the active ingredients of P.chinensis, provide appropriate guidance for clinical application, and provide a basis for the rational development and utilization of its resources.
查看全文   查看/发表评论  下载PDF阅读器
关闭
微信公众号
分享按钮