| Diarrhea-predominant irritable bowel syndrome (IBS-D) is one of the common clinical gastrointestinal diseases. In terms of treatment, modern medicine often adopts diet intervention, drug treatment and cognitive behavioral therapy, but there are many adverse reactions and easy to relapse, while traditional Chinese medicine treatment of IBS-D is safe and effective. At present, the interaction between gut microbiota and IBS-D has received extensive attention. This paper reviews the literature at home and abroad, and finds that gut microbiota, as a new intermediary of brain-gut interaction mechanism, plays an important role in immune system and neuroendocrine system. The traditional Chinese medicine compound can target the gut microbiota, affect the composition and structure of Firmicutes, Bacteroideta, Prevotella, Bifidobacterium, Lactobacillus, Escherichia coli and other gut microbiota, and effectively alleviate the clinical symptoms of IBS-D by reducing inflammation, inhibiting visceral hypersensitivity, restoring intestinal mucosal barrier, regulating gastrointestinal motility and other effects. |
